One of the most common scenarios for Topic Maps is to use them as the primary paradigm for organising, classifying and finding content in a content management system. The basic strategy involved in these integrations is to create topics for each content item in the CMS and then associate the content topics to other topics in the the topic map. We call this process 'content item proxification and classification'. This builds up a nice graph that can then be exploited in search and navigation controls either within the CMS or as part of some other publishing process.
Marc Kuster pointed me at a very positive article about the EGovShare protocol developed as part of a CEN work activity.
The Topic Map Constraint Language standard, which defines a way to create constraints/ schema for topic maps is moving into the final stages of the ISO process.
I recently did an interview for Tassilo Pellegrini from the Semantic Web Company. We talked about Topic Maps and the upcoming conference in Oslo. You can see the full interview here.
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NetworkedPlanet's Graham Moore and Kal Ahmed have contributed some new articles to the Microsoft Architecture Journal on the subject of topic maps and topic map applications.